You have no items in your shopping cart.
  • Chemical Products
  • Analytical Products
  • Purification Products
Featured products

1-Fluorocyclopropanecarboxylic acid

1-Fluorocyclopropanecarboxylic acid
CAS#: 137081-41-5
Size: 1g


CAS#: 1213269-23-8
Size: 5mg


CAS#: 110351-94-5

TLC Spotting Capillary Tubes

0.3mm ID, 100mm Length, 1000/PK

BARREL-SHAPED Filter Funnel with Celite

18 mL, 0.5 g Celite

Chiral Analytical HPLC Column

Venusil CA
5μm, 1000 Å

Flash Column, Silica

40-60μm, 60Å, 20g

Non-Sterile Syringe Filters

IC-Nylon Syringe Filters, 13mm, 0.22um, 200/PK


Size: 5mg


CAS#: 252917-06-9

Big News

Covalent Targeting of Fibroblast Growth Factor Receptor Inhibits Metastatic Breast Cancer

Abstract: We demonstrate that both b3 integrin and fibroblast growth factor receptor-1 (FGFR1) are part of an epithelial–mesenchymal transition (EMT) program that is required to facilitate metastatic outgrowth in response to fibroblast growth factor-2 (FGF2). Mechanistically, b3 integrin physically disru pts an interaction between FGFR1 and E-cadherin, leading to a dramatic redistribution of FGFR1 subcellular localization, enhanced FGF2 signaling and increased three-dimensional (3D) outgrowth of metastatic breast cancer cells. This ability of b3 integrin to drive FGFR signaling requires the enzymatic activity of focal adhesion kinase (FAK). Importantly, covalent targeting of a conserved cysteine in the P-loop of FGFR1–4 with our newly developed small molecule, FIIN-4(, more effectively blocks 3D metastatic outgrowth as compared with currently available FGFR inhibitors. In vivo application of FIIN-4 potently inhibited the growth of metastatic, patient-derived breast cancer xenografts and murine-derived metastases growing within the pulmonary microenvironment. More... 
Mol Cancer Ther; 15(9); 2096–106. 2016 AACR.




A ChemTek locates in Worcser MA provides chemicals, analytical, purification products and services to world-wide pharmaceutical researchers in an Easy, Economic, Efficient & Express way. The major products include Amino Acids, Bioactive Reference Compounds, Nature Products, Building Blocks; WE also distribute HPLC/prep-HPLC/flash columns, chromatography systems,  TLC, silica gel, syringe filters, vials etc.


Great news! The 2015 Fall ACS National Meeting and Exposition will open in August, 2015 at Boston Convention & Exhibition Center. A Chemtek Inc. will participate in the grand exhibition. Come and meet us at booth #914 then!


(Picture from